Cau 54: TB co che TD va AD lam sang cua cac thuoc dh van dong dg tieu hoa nhom khang dopamin ngoai bien

Thuoc khong dopamin ngoai bion: dan suat benzimidazol. Domperidon

Apromorphin la thuoc cuong dopamin tren he tieu hoa: kich thich trung tam non, lam tang nhu dong, da day, gay non

Domperidon la thuoc doi khang voi cac receptor cua DA chi o ngoai bien vo nu ko qua dc hang rao mau noo. Vo vay nu cu toc dung:

- chong non trung uong: uc che cac receptor dopamin o vung nhan cam hua hoc sàn noo that IV

- Lam tang toc do day chat chua trong da day xuong ruot non do: lam gion vung day da day. Lam tang co hang vi

- Chong lai trao nguoc thuc quan

- Dieu hua nhu dong duong tieu hoa

- Tang truong luc co that thuc quan

- Làm gion rong mun vi khi mo nhung ko lam roi loan van dong cua co that

- tang bien do va tan so cua nhu dong ta trang

Tac dung phu: nhuc dau, tang prolactin mau( chay sua, mon kinh, chung vy to o dan ong)

ADLS:

-ko dung lau dai va thuong xuyen

-Do cu toc dung ca tron trung uong, metoclopramid c o tac dung an than va co the gay phan ung loan truong